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| Ellen Burstyn | Sara Goldfarb | |
| Jennifer Connelly | Marion Silver | |
| Jared Leto | Harry Goldfarb | |
| Marlon Wayans | Tyrone C. Love | |
| Christopher McDonald | Tappy Tibbons | |
| Louise Lasser | Ada | |
| Marcia Jean Kurtz | Rae | |
| Janet Sarno | Mrs. Pearlman | |
| Suzanne Shepherd | Mrs. Scarlini | |
| Joanne Gordon | Mrs. Ovadia |
| Director |
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| Producer | Palmer West
Eric Watson |
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| Writer | Darren Aronofsky
Hubert Selby Jr. |
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| Cinematography | Matthew Libatique
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| Musician | Clint Mansell
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The hopes and dreams of four ambitious people are shattered when their drug addictions begin spiraling out of control. A look into addiction and how it overcomes the mind and body. |
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